GL1X · GenesisL1 explorer

Ligand · 4LK

4LK · 3-[3-fluoranyl-4-[5-methoxy-4-oxidanylidene-3-(2-phenylpyrazol-3-yl)pyridazin-1-yl]phenyl]-1,3-oxazolidin-2-one

4LK, 3-[3-fluoranyl-4-[5-methoxy-4-oxidanylidene-3-(2-phenylpyrazol-3-yl)pyridazin-1-yl]phenyl]-1,3-oxazolidin-2-one (C23 H18 F N5 O4, 447.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding…

Component
4LK
Formula
C23 H18 F N5 O4
Class
ligand
Structures
4
PDB entries
2

Binding sites

4LK in 4 structures; the first of them:

  • 5AXP · Crystal structure of the catalytic domain of PDE10A complexed with… · 4LK A1003 · binds TYR514, HIS515, ASP624, LEU625, ALA626, PHE629, ASP664, LEU665 and 8 more
  • 5AXQ · Crystal structure of the catalytic domain of PDE10A complexed with highly potent and… · 4LK B1003 · binds TYR514, HIS515, ASP624, LEU625, ALA626, PHE629, ASP664, LEU665 and 9 more
  • 5AXP · Crystal structure of the catalytic domain of PDE10A complexed with 1… · 4LK A1003 · binds TYR514, HIS515, ASP624, LEU625, ALA626, PHE629, ASP664, LEU665 and 8 more
  • 5AXQ · Crystal structure of the catalytic domain of PDE10A complexed with highly potent and… · 4LK B1003 · binds TYR514, HIS515, ASP624, LEU625, ALA626, PHE629, ASP664, LEU665 and 9 more

Residues it binds most

PHE 6, ASP 6, LEU 6, TYR 6, VAL 6, ALA 6, GLN 6, GLY 6, HIS 6, ILE 6 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • 4LP · 1-(cyclopropylmethyl)-4-fluoranyl-5-[5-methoxy-4-oxidanylidene-3-(2-phenylpyrazol-3-yl)pyridazin-1-yl]-3,3-dimethyl-indol-2-one

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.