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Ligand · 4LG

4LG · Methyl (6-{[(2R)-1-(4-{3-[(2-methoxybenzyl)oxy]propoxy}phenyl)-6-oxopiperazin-2-yl]methoxy}-1H-indol-1-yl)acetate

4LG, Methyl (6-{[(2R)-1-(4-{3-[(2-methoxybenzyl)oxy]propoxy}phenyl)-6-oxopiperazin-2-yl]methoxy}-1H-indol-1-yl)acetate (C33 H37 N3 O7, 587.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
4LG
Formula
C33 H37 N3 O7
Class
ligand
Structures
2
PDB entries
1

Binding sites

4LG in 2 structures; the first of them:

  • 2G27 · Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring · 4LG A804 · binds THR13, GLN14, TYR15, ASP33, GLY35, SER36, TRP40, PRO42 and 21 more
  • 2G27 · Ketopiperazine-based renin inhibitors: optimization of the "C" ring · 4LG B803 · binds THR13, GLN14, TYR15, ASP33, GLY35, SER36, TRP40, PRO42 and 19 more

Residues it binds most

ALA 4, ASP 4, GLY 4, VAL 4, TYR 4, PHE 4, PRO 4, SER 4, THR 4, GLN 4 (residue and the binding sites it lines).

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