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Ligand · 4L6

4L6 · 4-amino-8-(5-methyl-1H-indazol-6-yl)cinnoline-3-carboxamide

4L6, 4-amino-8-(5-methyl-1H-indazol-6-yl)cinnoline-3-carboxamide (C17 H14 N6 O, 318.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
4L6
Formula
C17 H14 N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

4L6 in 2 structures; the first of them:

  • 4Z3V · Fragment-Based Discovery of a Small Molecule Reversible Inhibitor of Bruton's Tyrosine… · 4L6 A705 · binds LEU408, GLY409, THR410, GLY411, GLN412, PHE413, GLY414, VAL416 and 13 more
  • 4Z3V · Fragment-based discovery of a small molecule reversible inhibitor of BRUTON'S tyrosine… · 4L6 A705 · binds LEU408, GLY409, THR410, GLY411, GLN412, PHE413, GLY414, VAL416 and 13 more

Residues it binds most

GLY 2, LEU 2, THR 2, ALA 2, ARG 2, ASN 2, ASP 2, CYS 2, GLN 2, GLU 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • IMD · Imidazole
  • IPA · Isopropyl alcohol

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