Ligand · 4HZ
4HZ · N~2~-[2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-yl]-N-(2,2,2-trifluoroethyl)-L-alaninamide
4HZ, N~2~-[2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-yl]-N-(2,2,2-trifluoroethyl)-L-alaninamide (C16 H13 Cl F4 N6 O, 416.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…
- Component
- 4HZ
- Formula
- C16 H13 Cl F4 N6 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
4HZ in 2 structures; the first of them:
- 4YTF · Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor… · 4HZ A4000 · binds LEU855, GLY856, LYS857, GLY858, VAL863, ALA880, VAL911, MET929 and 12 more
- 4YTF · Discovery of vx-509 (decernotinib): a potent and selective janus kinase (JAK) 3 inhibitor… · 4HZ A4000 · binds LEU855, GLY856, LYS857, GLY858, VAL863, ALA880, VAL911, MET929 and 12 more
Residues it binds most
GLY 2, LEU 2, ASP 2, VAL 2, ALA 2, ARG 2, ASN 2, GLU 2, ILE 2, LYS 2 (residue and the binding sites it lines).
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