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Ligand · 4H8

4H8 · 4-amino-2-[(2,2-dimethylpropyl)amino]pyrimidine-5-carboxamide

4H8, 4-amino-2-[(2,2-dimethylpropyl)amino]pyrimidine-5-carboxamide (C10 H17 N5 O, 223.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
4H8
Formula
C10 H17 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

4H8 in 2 structures; the first of them:

  • 4YQT · Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds · 4H8 A301 · binds TYR86, LEU87, SER88, PRO89, GLY113, ARG114, TYR115, GLU116 and 12 more
  • 4YQT · Crystal structure of trmd, a M1G37 tRNA methyltransferase with SAM- competitive compounds · 4H8 A301 · binds TYR86, LEU87, SER88, PRO89, GLY113, ARG114, TYR115, GLU116 and 12 more

Residues it binds most

GLY 2, TYR 2, LEU 2, PRO 2, SER 2, ARG 2, GLU 2, ILE 2, THR 2, TRP 2 (residue and the binding sites it lines).

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