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Ligand · 4H1

4H1 · 6-({[(1R,3S)-3-(aminomethyl)cyclohexyl]methyl}amino)pyridine-3-carboxamide

4H1, 6-({[(1R,3S)-3-(aminomethyl)cyclohexyl]methyl}amino)pyridine-3-carboxamide (C14 H22 N4 O, 262.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
4H1
Formula
C14 H22 N4 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

4H1 in 2 structures; the first of them:

  • 4YQO · Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds · 4H1 A301 · binds TYR86, LEU87, SER88, PRO89, GLY113, TYR115, GLU116, GLY117 and 11 more
  • 4YQO · Crystal structure of trmd, a M1G37 tRNA methyltransferase with SAM- competitive compounds · 4H1 A301 · binds TYR86, LEU87, SER88, PRO89, GLY113, TYR115, GLU116, GLY117 and 11 more

Residues it binds most

GLY 2, TYR 2, LEU 2, PRO 2, SER 2, GLU 2, ILE 2, THR 2, TRP 2, VAL 2 (residue and the binding sites it lines).

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