GL1X · GenesisL1 explorer

Ligand · 4FR

4FR · 3'-chloro-5'-[6-({2-methoxy-4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)-3-methyl-1H-pyrazolo[4,3-c]pyridin-1-yl]biphenyl-2-carboxamide

4FR, 3'-chloro-5'-[6-({2-methoxy-4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)-3-methyl-1H-pyrazolo[4,3-c]pyridin-1-yl]biphenyl-2-carboxamide (C34 H34 Cl N7 O3, 624.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records…

Component
4FR
Formula
C34 H34 Cl N7 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

4FR in 2 structures; the first of them:

  • 3DBE · Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain… · 4FR A1 · binds ARG43, PHE44, LEU45, GLY46, LYS47, GLY48, CYS53, ALA66 and 10 more
  • 3DBE · Crystal structure of an activated (thr->asp) polo-like kinase 1 (PLK1) catalytic domain… · 4FR A1 · binds ARG43, PHE44, LEU45, GLY46, LYS47, GLY48, CYS53, ALA66 and 10 more

Residues it binds most

ARG 2, CYS 2, GLY 2, LEU 2, LYS 2, PHE 2, ALA 2, GLU 2, ILE 2, VAL 2 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.