GL1X · GenesisL1 explorer

Ligand · 4E3

4E3 · 10-bromo-2-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acid

4E3, 10-bromo-2-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acid (C16 H8 Br I N2 O2, 467.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
4E3
Formula
C16 H8 Br I N2 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

4E3 in 2 structures; the first of them:

  • 4YLL · Crystal structure of DYRK1AA in complex with 10-Bromo-substituted… · 4E3 A515 · binds ILE165, GLY166, LYS167, PHE170, VAL173, ALA186, LYS188, GLU203 and 8 more
  • 4YLL · Crystal structure of DYRK1AA in complex with 10-bromo-substituted 11H… · 4E3 A515 · binds ILE165, GLY166, LYS167, PHE170, VAL173, ALA186, LYS188, GLU203 and 8 more

Residues it binds most

VAL 2, GLU 2, LEU 2, LYS 2, PHE 2, ALA 2, ASP 2, GLY 2, ILE 2, SER 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.