Ligand · 4B7
4B7 · 2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-N-(4-phenoxyphenyl)-1,3-thiazole-5-carboxamide
4B7, 2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-N-(4-phenoxyphenyl)-1,3-thiazole-5-carboxamide (C27 H29 N7 O3 S, 531.6 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every…
- Component
- 4B7
- Formula
- C27 H29 N7 O3 S
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
4B7 in 4 structures; the first of them:
- 4YBK · C-Helix-Out Dasatinib Analog Crystallized with c-Src Kinase · 4B7 A601 · binds LEU273, VAL281, ALA293, LYS295, MET314, VAL323, ILE336, THR338 and 12 more
- 4YC8 · C-Helix-Out Binding of Dasatinib Analog to c-Abl Kinase · 4B7 A601 · binds LEU248, VAL256, ALA269, LYS271, PHE283, GLU286, ALA287, MET290 and 10 more
- 4YBK · C-helix-out dasatinib analog crystallized with C-src kinase · 4B7 A601 · binds LEU273, VAL281, ALA293, LYS295, MET314, VAL323, ILE336, THR338 and 12 more
- 4YC8 · C-helix-out binding of dasatinib analog to C-abl kinase · 4B7 A601 · binds LEU248, VAL256, ALA269, LYS271, PHE283, GLU286, ALA287, MET290 and 10 more
Residues it binds most
LEU 6, PHE 6, ALA 6, MET 6, GLU 6, THR 6, LYS 6, VAL 6, GLY 6, ILE 6 (residue and the binding sites it lines).
Found with
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