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Ligand · 49J

49J · 2-methoxy-4-[3-(morpholin-4-yl)[1,2]thiazolo[4,3-b]pyridin-6-yl]aniline

49J, 2-methoxy-4-[3-(morpholin-4-yl)[1,2]thiazolo[4,3-b]pyridin-6-yl]aniline (C17 H18 N4 O2 S, 342.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
49J
Formula
C17 H18 N4 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

49J in 2 structures; the first of them:

  • 4Y8D · Crystal structure of Cyclin-G associated kinase (GAK) complexed with selective 12i… · 49J A401 · binds ARG44, LEU46, VAL54, ALA67, LYS69, MET89, VAL99, THR123 and 8 more
  • 4Y8D · Crystal structure of cyclin-G associated kinase (gak) complexed with selective 12I… · 49J A401 · binds ARG44, LEU46, VAL54, ALA67, LYS69, MET89, VAL99, THR123 and 8 more

Residues it binds most

LEU 4, CYS 4, LYS 4, VAL 4, ALA 4, ARG 4, GLU 4, GLY 4, THR 4, GLN 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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