Ligand · 49E
49E · 6-{[(1R)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
49E, 6-{[(1R)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (C18 H20 Cl N5 O, 357.8 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…
- Component
- 49E
- Formula
- C18 H20 Cl N5 O
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
49E in 4 structures; the first of them:
- 4Y86 · Crystal structure of PDE9 in complex with racemic inhibitor C33 · 49E B601 · binds PHE251, HIS252, MET365, ILE403, GLU406, LEU420, TYR424, PHE441 and 3 more
- 4Y87 · Crystal structure of phosphodiesterase 9 in complex with (R)-C33… · 49E A601 · binds PHE251, HIS252, MET365, ILE403, LEU420, TYR424, PHE441, ALA452 and 3 more
- 4Y86 · Crystal structure of PDE9 in complex with racemic inhibitor C33 · 49E B601 · binds PHE251, HIS252, MET365, ILE403, GLU406, LEU420, TYR424, PHE441 and 3 more
- 4Y87 · Crystal structure of phosphodiesterase 9 in complex with (R)-C33 (6… · 49E A601 · binds PHE251, HIS252, MET365, ILE403, LEU420, TYR424, PHE441, ALA452 and 3 more
Residues it binds most
PHE 6, ALA 6, GLN 6, HIS 6, ILE 6, LEU 6, MET 6, TYR 6, GLU 4, ASN 2 (residue and the binding sites it lines).
Found with
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