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Ligand · 481

481 · 4-tert-butyl-N-{3-[8-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)imidazo[1,2-a]pyrazin-6-yl]phenyl}benzamide

481, 4-tert-butyl-N-{3-[8-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)imidazo[1,2-a]pyrazin-6-yl]phenyl}benzamide (C35 H37 N7 O2, 587.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
481
Formula
C35 H37 N7 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

481 in 2 structures; the first of them:

  • 4OT5 · Crystal structure of BTK kinase domain complexed with… · 481 A701 · binds LEU408, GLY409, THR410, GLY411, GLN412, PHE413, VAL416, ALA428 and 18 more
  • 4OT5 · Crystal structure of btk kinase domain complexed with 4-tert-butyl-N… · 481 A701 · binds LEU408, GLY409, THR410, GLY411, GLN412, PHE413, VAL416, ALA428 and 18 more

Residues it binds most

GLY 2, LEU 2, ALA 2, ASN 2, ASP 2, GLU 2, THR 2, TYR 2, VAL 2, ARG 2 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide

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