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Ligand · 47I

47I · 4-[3-(4-piperazin-4-ium-1-ylphenyl)-1H-indazol-6-yl]phenol

47I, 4-[3-(4-piperazin-4-ium-1-ylphenyl)-1H-indazol-6-yl]phenol (C23 H23 N4 O +1, 371.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
47I
Formula
C23 H23 N4 O +1
Class
ligand
Structures
2
PDB entries
2

Binding sites

47I in 2 structures; the first of them:

  • 7OZB · FGFR1 kinase domain (residues 458-765) with mutations C488A, C584S in complex with 38. · 47I AAA801 · binds LEU484, VAL492, ALA512, LYS514, GLU531, ILE545, VAL561, GLU562 and 9 more
  • 7OZY · FGFR2 kinase domain (residues 461-763) in complex with 38. · 47I AAA801 · binds LEU487, VAL495, ALA515, LYS517, GLU534, VAL564, GLU565, TYR566 and 6 more

Residues it binds most

GLU 4, LEU 4, ALA 4, VAL 4, LYS 4, ASP 4, GLY 4, SER 4, TYR 4, ILE 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol

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