GL1X · GenesisL1 explorer

Ligand · 47D

47D · {3-[(5-chloro-1,3-benzothiazol-2-yl)methyl]-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}acetic acid

47D, {3-[(5-chloro-1,3-benzothiazol-2-yl)methyl]-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}acetic acid (C14 H10 Cl N3 O4 S, 351.8 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its…

Component
47D
Formula
C14 H10 Cl N3 O4 S
Class
ligand
Structures
8
PDB entries
4

Binding sites

47D in 8 structures; the first of them:

  • 2PDG · Human aldose reductase with uracil-type inhibitor at 1.42A. · 47D A600 · binds TRP20, TYR48, TRP79, HIS110, TRP111, THR113, PHE115, PHE122 and 7 more
  • 2PDH · Human aldose reductase mutant L300P complexed with uracil-type inhibitor at 1.45 A. · 47D A600 · binds TRP20, TYR48, TRP79, CYS80, HIS110, TRP111, THR113, PHE115 and 7 more
  • 2PDN · Human aldose reductase mutant S302R complexed with uracil-type inhibitor. · 47D A600 · binds TRP20, TYR48, TRP79, CYS80, HIS110, TRP111, THR113, PHE115 and 8 more
  • 2PDQ · Human aldose reductase mutant C303D complexed with uracil-type inhibitor. · 47D A600 · binds TRP20, TYR48, TRP79, CYS80, HIS110, TRP111, THR113, PHE115 and 8 more
  • 2PDG · Human aldose reductase with uracil-type inhibitor at 1.42A. · 47D A600 · binds TRP20, TYR48, TRP79, HIS110, TRP111, THR113, PHE115, PHE122 and 7 more
  • 2PDH · Human aldose reductase mutant L300P complexed with uracil-type inhibitor at 1.45 a. · 47D A600 · binds TRP20, TYR48, TRP79, CYS80, HIS110, TRP111, THR113, PHE115 and 7 more
  • 2PDN · Human aldose reductase mutant S302R complexed with uracil-type inhibitor. · 47D A600 · binds TRP20, TYR48, TRP79, CYS80, HIS110, TRP111, THR113, PHE115 and 8 more
  • 2PDQ · Human aldose reductase mutant C303D complexed with uracil-type inhibitor. · 47D A600 · binds TRP20, TYR48, TRP79, CYS80, HIS110, TRP111, THR113, PHE115 and 8 more

Residues it binds most

TRP 8, CYS 8, PHE 8, TYR 8, PRO 8, HIS 8, THR 8, ALA 6, LEU 6, ASP 2 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.