Ligand · 436

436 · (2S)-N-{(2R)-1-[(2R,4S)-2-{[6,6'-difluoro-3'-({(2R,4S)-4-hydroxy-1-[(2S)-2-{[(2S)-2-(methylamino)propanoyl]amino}butanoyl]pyrrolidin-2-yl}methyl)-1H,1'H-2,2'-biindol-3-yl]methyl}-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl}-2-(methylamino)propanamide

436, (2S)-N-{(2R)-1-[(2R,4S)-2-{[6,6'-difluoro-3'-({(2R,4S)-4-hydroxy-1-[(2S)-2-{[(2S)-2-(methylamino)propanoyl]amino}butanoyl]pyrrolidin-2-yl}methyl)-1H,1'H-2,2'-biindol-3-yl]methyl}-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl}-2-(methylamin…

Component: 436
Formula: C42 H56 F2 N8 O6
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

436 in 2 structures; the first of them:

4KMN · Structure of cIAP1-BIR3 and inhibitor · 436 A502 · binds VAL292, ARG294, ASP297, VAL298, LYS299, GLY306, LEU307, ARG308 and 7 more
4KMN · Structure of CIAP1-BIR3 and inhibitor · 436 A502 · binds VAL292, ARG294, ASP297, VAL298, LYS299, GLY306, LEU307, ARG308 and 7 more

Residues it binds most

ARG 2, ASP 2, GLU 2, TRP 2, VAL 2, CYS 2, GLY 2, LEU 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

ZN · Zinc ion
PO4 · Phosphate ion

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