GL1X · GenesisL1 explorer

Ligand · 41B

41B · 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-(tetrahydro-2H-pyran-4-ylamino)pyrimidin-4-yl]pyridin-2(1H)-one

41B, 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-(tetrahydro-2H-pyran-4-ylamino)pyrimidin-4-yl]pyridin-2(1H)-one (C22 H22 Cl F N4 O3, 444.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
41B
Formula
C22 H22 Cl F N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

41B in 2 structures; the first of them:

  • 4XJ0 · Crystal structure of ERK2 in complex with an inhibitor 14K · 41B A401 · binds ILE31, GLY32, GLU33, GLY34, GLY37, MET38, VAL39, ALA52 and 16 more
  • 4XJ0 · Crystal structure of ERK2 in complex with an inhibitor 14K · 41B A401 · binds ILE31, GLY32, GLU33, GLY34, GLY37, MET38, VAL39, ALA52 and 16 more

Residues it binds most

ASP 4, GLU 4, GLY 4, ILE 4, LEU 4, LYS 4, MET 4, ALA 4, ASN 4, CYS 4 (residue and the binding sites it lines).

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