GL1X · GenesisL1 explorer

Ligand · 3ZP

3ZP · 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-4-(dimethylamino)-5-[(2S,4R,5S,6S)-4,6-dimethyl-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-methyl-3-oxidanyl-oxan-2-yl]oxy-16-ethyl-15-[[(2R,3R,4R,5S,6R)-3-methoxy-6-methyl-4,5-bis(oxidanyl)oxan-2-yl]oxymethyl]-5,9,13-trimethyl-4-oxidanyl-2,10-bis(oxidanylidene)-1-oxacyclohexadeca-11,13-dien-7-yl]ethanal

3ZP, 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-4-(dimethylamino)-5-[(2S,4R,5S,6S)-4,6-dimethyl-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-methyl-3-oxidanyl-oxan-2-yl]oxy-16-ethyl-15-[[(2R,3R,4R,5S,6R)-3-methoxy-6-methyl-4,5-bis(oxidanyl…

Component
3ZP
Formula
C45 H75 N O17
Class
ligand
Structures
2
PDB entries
1

Binding sites

3ZP in 2 structures; the first of them:

  • 4X7X · MycF mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with Mg, SAH… · 3ZP A303 · binds ALA30, GLY31, LEU32, TYR49, MET56, ARG61, PHE118, MET132 and 12 more
  • 4X7X · Mycf mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with mg, sah… · 3ZP A303 · binds ALA30, GLY31, LEU32, TYR49, MET56, ARG61, PHE118, MET132 and 12 more

Residues it binds most

ASP 4, LEU 4, MET 4, TYR 4, ALA 4, ARG 4, CYS 4, GLN 4, GLY 4, ILE 4 (residue and the binding sites it lines).

Found with

  • SAH · S-adenosyl-L-homocysteine
  • MG · Magnesium ion

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