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Ligand · 3U6

3U6 · 6-[5-(5-amino-1,3,4-thiadiazol-2-yl)-1H-indol-3-yl]-N-cyclopentylpyridin-2-amine

3U6, 6-[5-(5-amino-1,3,4-thiadiazol-2-yl)-1H-indol-3-yl]-N-cyclopentylpyridin-2-amine (C20 H20 N6 S, 376.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
3U6
Formula
C20 H20 N6 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

3U6 in 2 structures; the first of them:

  • 4WT6 · Crystal structure of human Pim-1 kinase in complex with a thiadiazolamine-indole… · 3U6 A401 · binds LEU44, GLY45, SER46, PHE49, VAL52, ALA65, LYS67, ILE104 and 9 more
  • 4WT6 · Crystal structure of human pim-1 kinase in complex with a thiadiazolamine-indole… · 3U6 A401 · binds LEU44, GLY45, SER46, PHE49, VAL52, ALA65, LYS67, ILE104 and 9 more

Residues it binds most

LEU 2, ASP 2, ILE 2, VAL 2, ALA 2, ARG 2, GLU 2, GLY 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

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