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Ligand · 3U5

3U5 · 5-[3-(quinolin-3-yl)-2H-indazol-5-yl]-1,3-thiazol-2-amine

3U5, 5-[3-(quinolin-3-yl)-2H-indazol-5-yl]-1,3-thiazol-2-amine (C19 H13 N5 S, 343.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
3U5
Formula
C19 H13 N5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

3U5 in 2 structures; the first of them:

  • 4WSY · Crystal structure of human Pim-1 kinase in complex with a thiazolamine-indazole inhibitor. · 3U5 A401 · binds LEU44, PHE49, VAL52, ALA65, LYS67, ILE104, LEU120, GLU121 and 6 more
  • 4WSY · Crystal structure of human pim-1 kinase in complex with a thiazolamine-indazole inhibitor. · 3U5 A401 · binds LEU44, PHE49, VAL52, ALA65, LYS67, ILE104, LEU120, GLU121 and 6 more

Residues it binds most

LEU 2, ILE 2, VAL 2, ALA 2, ARG 2, ASP 2, GLU 2, LYS 2, PHE 2, PRO 2 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

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