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Ligand · 3TK

3TK · N-(5-benzyl-1,3-thiazol-2-yl)-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamide

3TK, N-(5-benzyl-1,3-thiazol-2-yl)-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamide (C18 H18 N4 O S2, 370.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
3TK
Formula
C18 H18 N4 O S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

3TK in 2 structures; the first of them:

  • 4RMI · Human Sirt2 in complex with SirReal1 and Ac-Lys-OTC peptide · 3TK A402 · binds ILE93, PHE96, PHE119, PHE131, LEU134, ALA135, LEU138, TYR139 and 10 more
  • 4RMI · Human SIRT2 in complex with SIRREAL1 and ac-lys-otc peptide · 3TK A402 · binds ILE93, PHE96, PHE119, PHE131, LEU134, ALA135, LEU138, TYR139 and 10 more

Residues it binds most

PHE 2, ILE 2, LEU 2, ALA 2, ALY 2, ASP 2, PRO 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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