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Ligand · 3TC

3TC · 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one

3TC, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one (C8 H11 N3 O3 S, 229.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
3TC
Formula
C8 H11 N3 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

3TC in 2 structures; the first of them:

  • 2NOA · The structure of deoxycytidine kinase complexed with lamivudine and ADP. · 3TC A302 · binds ILE30, GLU53, VAL55, TRP58, LEU82, MET85, TYR86, PHE96 and 9 more
  • 2NOA · The structure of deoxycytidine kinase complexed with lamivudine and ADP. · 3TC A302 · binds ILE30, GLU53, VAL55, TRP58, LEU82, MET85, TYR86, PHE96 and 9 more

Residues it binds most

ARG 4, GLU 4, PHE 4, TYR 4, ALA 4, ASP 4, GLN 4, ILE 4, LEU 4, MET 4 (residue and the binding sites it lines).

Found with

  • ADP · Adenosine-5'-diphosphate

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