GL1X · GenesisL1 explorer

Ligand · 3RH

3RH · (6S)-6-phenyl-5,6-dihydrobenzo[h]quinazolin-2-amine

3RH, (6S)-6-phenyl-5,6-dihydrobenzo[h]quinazolin-2-amine (C18 H15 N3, 273.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
3RH
Formula
C18 H15 N3
Class
ligand
Structures
4
PDB entries
2

Binding sites

3RH in 4 structures; the first of them:

  • 3RHX · Crystal structure of the catalytic domain of FGFR1 kinase in complex with ARQ 069 · 3RH B1 · binds LEU484, GLY485, PHE489, VAL492, ALA512, LYS514, GLU531, MET535 and 8 more
  • 3RI1 · Crystal structure of the catalytic domain of FGFR2 kinase in complex with ARQ 069 · 3RH A2 · binds LEU487, GLY488, VAL495, ALA515, LYS517, GLU534, MET538, ILE548 and 8 more
  • 3RHX · Crystal structure of the catalytic domain of FGFR1 kinase in complex with arq 069 · 3RH B1 · binds LEU484, GLY485, PHE489, VAL492, ALA512, LYS514, GLU531, MET535 and 8 more
  • 3RI1 · Crystal structure of the catalytic domain of FGFR2 kinase in complex with arq 069 · 3RH A2 · binds LEU487, GLY488, VAL495, ALA515, LYS517, GLU534, MET538, ILE548 and 8 more

Residues it binds most

ALA 8, GLU 8, LEU 8, VAL 8, GLY 6, ASP 8, ILE 8, LYS 8, MET 8, TYR 8 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.