GL1X · GenesisL1 explorer

Ligand · 3QY

3QY · N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine

3QY, N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine (C20 H22 N8 O, 390.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
3QY
Formula
C20 H22 N8 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

3QY in 2 structures; the first of them:

  • 4RJ5 · EGFR kinase (T790M/L858R) with inhibitor compound 5 · 3QY A1101 · binds LEU718, GLY719, PHE723, VAL726, ALA743, LYS745, GLU762, MET766 and 9 more
  • 4RJ5 · EGFR kinase (T790M/L858R) with inhibitor compound 5 · 3QY A1101 · binds LEU718, GLY719, PHE723, VAL726, ALA743, LYS745, GLU762, MET766 and 9 more

Residues it binds most

LEU 2, MET 2, GLY 2, ALA 2, ASP 2, GLN 2, GLU 2, LYS 2, PHE 2, PRO 2 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.