GL1X · GenesisL1 explorer

Ligand · 3LH

3LH · N-{2-methyl-5-[2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl]phenyl}propanamide

3LH, N-{2-methyl-5-[2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl]phenyl}propanamide (C25 H21 N5 O2, 423.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
3LH
Formula
C25 H21 N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

3LH in 2 structures; the first of them:

  • 4WD5 · Crystal structure of EGFR 696-1022 T790M in complex with QL-X138 · 3LH A1101 · binds LEU718, GLY719, VAL726, ALA743, MET790, GLN791, LEU792, MET793 and 8 more
  • 4WD5 · Crystal structure of EGFR 696-1022 T790M in complex with ql-X138 · 3LH A1101 · binds LEU718, GLY719, VAL726, ALA743, MET790, GLN791, LEU792, MET793 and 8 more

Residues it binds most

LEU 2, GLY 2, MET 2, ALA 2, ARG 2, ASP 2, CYS 2, GLN 2, PRO 2, THR 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.