GL1X · GenesisL1 explorer

Ligand · 3J5

3J5 · 2-(4-{6-[(3S)-3,4-dimethylpiperazin-1-yl]-4-methylpyridin-3-yl}phenyl)-8-(hydroxymethyl)quinazolin-4(3H)-one

3J5, 2-(4-{6-[(3S)-3,4-dimethylpiperazin-1-yl]-4-methylpyridin-3-yl}phenyl)-8-(hydroxymethyl)quinazolin-4(3H)-one (C27 H29 N5 O2, 455.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
3J5
Formula
C27 H29 N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

3J5 in 2 structures; the first of them:

  • 4W6E · Human Tankyrase 1 with small molecule inhibitor · 3J5 A1402 · binds PHE1183, HIS1184, GLY1185, SER1186, PRO1187, PHE1188, HIS1201, ALA1202 and 10 more
  • 4W6E · Human tankyrase 1 with small molecule inhibitor · 3J5 A1402 · binds PHE1183, HIS1184, GLY1185, SER1186, PRO1187, PHE1188, HIS1201, ALA1202 and 10 more

Residues it binds most

PHE 2, TYR 2, ALA 2, GLY 2, HIS 2, SER 2, GLU 2, ILE 2, LYS 2, PRO 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.