3IN · N-[2(S)-cyclopentyl-1(R)-hydroxy-3(r)methyl]-5-[(2(S)-tertiary-butylamino-carbonyl)-4-(N1-(2)-(N-methylpiperazinyl)-3-chloro-pyrazinyl-5-carbonyl)-piperazino]-4(S)-hydroxy-2(R)-phenylmethyl-pentanamide

Binding sites

3IN in 6 structures; the first of them:

• 1C6X · Alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors… · 3IN B622 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 21 more
• 2BPY · HIV-1 protease-inhibitor complex · 3IN B902 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 23 more
• 2BPZ · HIV-1 protease-inhibitor complex · 3IN B902 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 23 more
• 1C6X · Alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors… · 3IN B622 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 21 more
• 2BPY · HIV-1 protease-inhibitor complex · 3IN B902 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 23 more
• 2BPZ · HIV-1 protease-inhibitor complex · 3IN B902 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 23 more

Residues it binds most

ASP 6, GLY 6, ILE 6, VAL 6, ALA 6, ARG 6, PRO 6, LEU 6, PHE 6, THR 2 (residue and the binding sites it lines).