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Ligand · 3G7

3G7 · (3R)-1-{2-[4-(4-acetylphenyl)piperazin-1-yl]-2-oxoethyl}-N-(3-chloro-4-hydroxyphenyl)pyrrolidine-3-carboxamide

3G7, (3R)-1-{2-[4-(4-acetylphenyl)piperazin-1-yl]-2-oxoethyl}-N-(3-chloro-4-hydroxyphenyl)pyrrolidine-3-carboxamide (C25 H29 Cl N4 O4, 485.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
3G7
Formula
C25 H29 Cl N4 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

3G7 in 2 structures; the first of them:

  • 4QYY · Discovery of Novel, Dual Mechanism ERK Inhibitors by Affinity Selection Screening of an… · 3G7 A401 · binds ILE29, ALA33, TYR34, VAL37, ALA50, LYS52, ILE54, TYR62 and 12 more
  • 4QYY · Discovery of novel, dual mechanism ERK inhibitors by affinity selection screening of an… · 3G7 A401 · binds ILE29, ALA33, TYR34, VAL37, ALA50, LYS52, ILE54, TYR62 and 12 more

Residues it binds most

ILE 2, ALA 2, ASP 2, LEU 2, TYR 2, ARG 2, CYS 2, GLN 2, GLU 2, GLY 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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