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Ligand · 3F4

3F4 · 2-(4-hydroxyphenyl)-3H-quinazolin-4-one

3F4, 2-(4-hydroxyphenyl)-3H-quinazolin-4-one (C14 H10 N2 O2, 238.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
3F4
Formula
C14 H10 N2 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

3F4 in 2 structures; the first of them:

  • 4BU5 · Crystal structure of human tankyrase 2 in complex with 2-(4… · 3F4 A2162 · binds PHE1030, HIS1031, GLY1032, SER1033, PRO1034, PHE1035, HIS1048, ALA1049 and 9 more
  • 4BU5 · Crystal structure of human tankyrase 2 in complex with 2-(4… · 3F4 A2162 · binds PHE1030, HIS1031, GLY1032, SER1033, PRO1034, PHE1035, HIS1048, ALA1049 and 9 more

Residues it binds most

PHE 4, TYR 4, ALA 4, HIS 4, SER 4, GLU 4, GLY 4, ILE 4, LYS 4, PRO 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • GOL · Glycerol
  • PEG · Di(hydroxyethyl)ether

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