Ligand · 390

390 · 4-{2-[(2-chloro-4-fluorophenyl)amino]-5-methylpyrimidin-4-yl}-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide

390, 4-{2-[(2-chloro-4-fluorophenyl)amino]-5-methylpyrimidin-4-yl}-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide (C24 H20 Cl2 F N5 O2, 500.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component: 390
Formula: C24 H20 Cl2 F N5 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

390 in 2 structures; the first of them:

6OPK · Phosphorylated ERK2 with Vertex-11e · 390 A401 · binds ILE29, GLU31, GLY32, TYR34, GLY35, MET36, VAL37, ALA50 and 11 more
6OPK · Phosphorylated ERK2 with vertex-11E · 390 A401 · binds ILE29, GLU31, GLY32, TYR34, GLY35, MET36, VAL37, ALA50 and 11 more

Residues it binds most

ASP 2, GLU 2, GLY 2, LEU 2, LYS 2, MET 2, ALA 2, ASN 2, GLN 2, ILE 2 (residue and the binding sites it lines).

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