Ligand · 38R
38R · [4-({4-[(3-cyclopentyl-1H-pyrazol-5-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrile
38R, [4-({4-[(3-cyclopentyl-1H-pyrazol-5-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrile (C20 H21 N7, 359.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within…
- Component
- 38R
- Formula
- C20 H21 N7
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
38R in 4 structures; the first of them:
- 3ZDU · Crystal structure of the human CDKL3 kinase domain · 38R A350 · binds VAL10, GLY11, TYR15, VAL18, ALA31, LYS33, VAL63, PHE79 and 12 more
- 4BGQ · Crystal structure of the human CDKL5 kinase domain · 38R A1000 · binds VAL19, TYR24, VAL27, ALA40, LYS42, VAL73, PHE89, GLU90 and 10 more
- 3ZDU · Crystal structure of the human CDKL3 kinase domain · 38R A350 · binds VAL10, GLY11, TYR15, VAL18, ALA31, LYS33, VAL63, PHE79 and 12 more
- 4BGQ · Crystal structure of the human CDKL5 kinase domain · 38R A1000 · binds VAL19, TYR24, VAL27, ALA40, LYS42, VAL73, PHE89, GLU90 and 10 more
Residues it binds most
VAL 4, GLU 4, ASP 4, LYS 4, PHE 4, TYR 4, ALA 4, ASN 4, CYS 4, LEU 4 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.