Ligand · 36H

36H · 2-((1-(2-fluoro-4-((4-(1-isopropyl-1H-pyrazol-4-yl)-5-methylpyrimidin-2-yl)amino)phenyl)piperidin-4-yl) (methyl)amino)ethan-1-ol

36H, 2-((1-(2-fluoro-4-((4-(1-isopropyl-1H-pyrazol-4-yl)-5-methylpyrimidin-2-yl)amino)phenyl)piperidin-4-yl) (methyl)amino)ethan-1-ol (C25 H34 F N7 O, 467.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component: 36H
Formula: C25 H34 F N7 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

36H in 2 structures; the first of them:

7F7W · JAK2-JH2 · 36H A1000 · binds LEU551, GLN553, GLY554, ILE559, LEU579, LYS581, VAL610, GLN626 and 10 more
7F7W · JAK2-JH2 · 36H A1000 · binds LEU551, GLN553, GLY554, ILE559, LEU579, LYS581, VAL610, GLN626 and 8 more

Residues it binds most

LEU 4, LYS 4, GLN 4, GLY 4, VAL 4, SER 4, PHE 4, GLU 4, ILE 4, ASN 1 (residue and the binding sites it lines).

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