GL1X · GenesisL1 explorer

Ligand · 35T

35T · {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-(pyrrolidin-1-ylsulfonyl)ethyl]-3-methyl-2-oxopiperidin-3-yl}acetic acid

35T, {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-(pyrrolidin-1-ylsulfonyl)ethyl]-3-methyl-2-oxopiperidin-3-yl}acetic acid (C29 H34 Cl2 N2 O5 S, 593.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
35T
Formula
C29 H34 Cl2 N2 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

35T in 2 structures; the first of them:

  • 4QOC · crystal structure of compound 16 bound to MDM2(17-111)… · 35T A201 · binds LEU54, LEU57, GLY58, GLN59, ILE61, MET62, TYR67, VAL75 and 7 more
  • 4QOC · Crystal structure of compound 16 bound to MDM2(17-111), {(3R,5R,6S)-5… · 35T A201 · binds LEU54, LEU57, GLY58, GLN59, ILE61, MET62, TYR67, VAL75 and 7 more

Residues it binds most

PHE 12, ILE 12, LEU 12, TYR 12, VAL 12, LYS 12, GLN 10, GLY 12, HIS 12, MET 12 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.