GL1X · GenesisL1 explorer

Ligand · 33I

33I · 6-(4-amino-4-methylpiperidin-1-yl)-3-(3-chlorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

33I, 6-(4-amino-4-methylpiperidin-1-yl)-3-(3-chlorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (C17 H19 Cl N6 O, 358.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
33I
Formula
C17 H19 Cl N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

33I in 2 structures; the first of them:

  • 7R75 · Structure of human SHP2 in complex with compound 16 · 33I A601 · binds THR108, GLU110, ARG111, PHE113, HIS114, ASN217, THR218, THR219 and 9 more
  • 7R75 · Structure of human SHP2 in complex with compound 16 · 33I A601 · binds THR108, GLU110, ARG111, PHE113, HIS114, ASN217, THR218, THR219 and 7 more

Residues it binds most

THR 2, GLU 2, GLN 2, ARG 2, ASN 2, HIS 2, LEU 2, LYS 2, PHE 2, PRO 2 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.