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Ligand · 319

319 · N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide

319, N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide (C20 H16 F2 N4 O3, 398.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
319
Formula
C20 H16 F2 N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

319 in 2 structures; the first of them:

  • 3CTH · Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor… · 319 A2001 · binds ILE1084, VAL1092, ALA1108, LYS1110, GLU1127, ILE1130, MET1131, PHE1134 and 16 more
  • 3CTH · Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor… · 319 A2001 · binds ILE1084, VAL1092, ALA1108, LYS1110, GLU1127, ILE1130, MET1131, PHE1134 and 16 more

Residues it binds most

VAL 2, LEU 2, MET 2, PHE 2, ALA 2, ILE 2, ASP 2, GLU 2, GLY 2, HIS 2 (residue and the binding sites it lines).

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