Ligand · 2YE

2YE · 2-amino-N,N-dimethyl-5-(1H-pyrrolo[2,3-b]pyridin-5-yl) benzamide

2YE, 2-amino-N,N-dimethyl-5-(1H-pyrrolo[2,3-b]pyridin-5-yl) benzamide (C16 H16 N4 O, 280.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component: 2YE
Formula: C16 H16 N4 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

2YE in 2 structures; the first of them:

7R9L · Crystal structure of HPK1 in complex with compound 2 · 2YE A301 · binds GLN21, ARG22, LEU23, GLY24, TYR28, ALA44, VAL75, MET91 and 9 more
7R9L · Crystal structure of HPK1 in complex with compound 2 · 2YE A301 · binds LEU23, GLY24, TYR28, ALA44, MET91, GLU92, PHE93, CYS94 and 5 more

Residues it binds most

GLY 2, LEU 2, ALA 2, ASP 2, CYS 2, GLU 2, MET 2, PHE 2, SER 2, TYR 2 (residue and the binding sites it lines).

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