Ligand · 2WI

2WI · 6-amino-2-fluoro-N,N-dimethyl-3-(4'-methylspiro[cyclopropane-1,3'-pyrrolo[2,3-b]pyridin]-5'-yl)benzamide

2WI, 6-amino-2-fluoro-N,N-dimethyl-3-(4'-methylspiro[cyclopropane-1,3'-pyrrolo[2,3-b]pyridin]-5'-yl)benzamide (C19 H19 F N4 O, 338.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component: 2WI
Formula: C19 H19 F N4 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

2WI in 2 structures; the first of them:

7R9P · Crystal structure of HPK1 in complex with compound 14 · 2WI A301 · binds GLN21, ARG22, LEU23, GLY24, TYR28, VAL31, ALA44, VAL75 and 11 more
7R9P · Crystal structure of HPK1 in complex with compound 14 · 2WI A301 · binds GLN21, LEU23, GLY24, TYR28, VAL31, ALA44, VAL75, MET91 and 9 more

Residues it binds most

GLY 4, ALA 4, LEU 4, VAL 4, ASP 4, CYS 4, GLU 4, MET 4, PHE 4, SER 4 (residue and the binding sites it lines).

Found with

SO4 · Sulfate ion

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