2VN · 2-[(4-{2-[(4-cyclohexylbutyl)(cyclohexylcarbamoyl) amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid

Binding sites

2VN in 7 structures; the first of them:

• 6KAY · X-ray structure of human PPARalpha ligand binding domain-GW7647 co-crystals obtained by… · 2VN A501 · binds LEU247, PHE273, CYS275, CYS276, GLN277, THR279, SER280, THR283 and 13 more
• 6KB3 · X-ray structure of human PPARalpha ligand binding domain-GW7647 co-crystals obtained by… · 2VN A502 · binds LEU247, PHE273, CYS276, GLN277, THR279, SER280, THR283, TYR314 and 9 more
• 6DRG · NMR solution structure of wild type HFABP1 with GW7647 · 2VN A201 · binds LEU9, GLY37, VAL38, SER39, PHE48, PHE50, ILE52, THR53 and 13 more
• 6KAY · X-ray structure of human pparalpha ligand binding domain-GW7647 co- crystals obtained by… · 2VN A501 · binds LEU247, PHE273, CYS275, CYS276, GLN277, THR279, SER280, THR283 and 13 more
• 6KB3 · X-ray structure of human pparalpha ligand binding domain-GW7647 co- crystals obtained by… · 2VN A502 · binds LEU247, PHE273, CYS276, GLN277, THR279, SER280, THR283, TYR314 and 9 more
• 6KB8 · X-ray structure of human pparalpha ligand binding domain-GW7647 co- crystals obtained by… · 2VN A502 · binds LEU247, PHE273, CYS275, CYS276, GLN277, THR279, SER280, THR283 and 11 more
• 7BQ3 · X-ray structure of human pparalpha ligand binding domain-GW7647-SRC1 coactivator peptide… · 2VN A501 · binds ILE241, LEU247, VAL255, PHE273, CYS276, GLN277, THR279, SER280 and 10 more

Residues it binds most

LEU 7, ILE 7, MET 7, THR 7, TYR 6, VAL 7, PHE 7, CYS 6, SER 7, GLN 6 (residue and the binding sites it lines).

Found with

• GOL · Glycerol