Ligand · 2U7

2U7 · [(2S,5R,6R)-4-[(2S)-1-(tert-butylsulfonyl)butan-2-yl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid

2U7, [(2S,5R,6R)-4-[(2S)-1-(tert-butylsulfonyl)butan-2-yl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid (C26 H31 Cl2 N O6 S, 556.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component: 2U7
Formula: C26 H31 Cl2 N O6 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

2U7 in 2 structures; the first of them:

4OGV · Co-Crystal Structure of MDM2 with Inhibitor Compound 49 · 2U7 A501 · binds GLN24, LEU54, LEU57, GLY58, ILE61, MET62, TYR67, PHE86 and 8 more
4OGV · Co-crystal structure of MDM2 with inhibitor compound 49 · 2U7 A501 · binds GLN24, LEU54, LEU57, GLY58, ILE61, MET62, TYR67, PHE86 and 8 more

Residues it binds most

ILE 6, LEU 6, PHE 6, TYR 6, GLN 6, GLY 6, HIS 6, MET 6, VAL 6, LYS 4 (residue and the binding sites it lines).

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