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Ligand · 2U6

2U6 · 6-{[(2R,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-2-methyl-3-oxomorpholin-2-yl]methyl}pyridine-3-carboxylic acid

2U6, 6-{[(2R,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-2-methyl-3-oxomorpholin-2-yl]methyl}pyridine-3-carboxylic acid (C33 H36 Cl2 N2 O6 S, 659.6 g/mol), in the MolNFT structures on…

Component
2U6
Formula
C33 H36 Cl2 N2 O6 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

2U6 in 2 structures; the first of them:

  • 4OGT · Co-Crystal Structure of MDM2 with Inhbitor Compound 46 · 2U6 A201 · binds VAL14, THR15, THR16, GLN18, LEU54, LEU57, GLY58, ILE61 and 10 more
  • 4OGT · Co-crystal structure of MDM2 with inhbitor compound 46 · 2U6 A201 · binds VAL14, THR15, THR16, GLN18, LEU54, LEU57, GLY58, ILE61 and 10 more

Residues it binds most

VAL 2, HIS 2, ILE 2, LEU 2, THR 2, TYR 2, GLN 2, GLY 2, LYS 2, MET 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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