GL1X · GenesisL1 explorer

Ligand · 2U1

2U1 · 6-{[(2S,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-2-methyl-3-oxomorpholin-2-yl]methyl}pyridine-3-carboxylic acid

2U1, 6-{[(2S,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-2-methyl-3-oxomorpholin-2-yl]methyl}pyridine-3-carboxylic acid (C33 H36 Cl2 N2 O6 S, 659.6 g/mol), in the MolNFT structures on…

Component
2U1
Formula
C33 H36 Cl2 N2 O6 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

2U1 in 2 structures; the first of them:

  • 4ODF · Co-Crystal Structure of MDM2 with Inhibitor Compound 47 · 2U1 A201 · binds VAL14, THR15, THR16, SER17, LEU54, LEU57, GLY58, ILE61 and 9 more
  • 4ODF · Co-crystal structure of MDM2 with inhibitor compound 47 · 2U1 A201 · binds VAL14, THR15, THR16, SER17, LEU54, LEU57, GLY58, ILE61 and 9 more

Residues it binds most

VAL 2, ILE 2, LEU 2, PHE 2, THR 2, TYR 2, GLY 2, HIS 2, MET 2, SER 2 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.