Ligand · 2TW

2TW · [(2R,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid

2TW, [(2R,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid (C27 H31 Cl2 N O6 S, 568.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component: 2TW
Formula: C27 H31 Cl2 N O6 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

2TW in 2 structures; the first of them:

4OBA · Co-crystal structure of MDM2 with Inhibitor Compound 4 · 2TW A501 · binds LEU54, PHE55, LEU57, GLY58, GLN59, ILE61, MET62, TYR67 and 10 more
4OBA · Co-crystal structure of MDM2 with inhibitor compound 4 · 2TW A501 · binds LEU54, PHE55, LEU57, GLY58, GLN59, ILE61, MET62, TYR67 and 10 more

Residues it binds most

PHE 6, ILE 6, LEU 6, TYR 6, VAL 6, GLN 6, GLY 6, HIS 6, LYS 6, MET 6 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.