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Ligand · 2TU

2TU · 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

2TU, 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (C9 H12 N2 O5 S, 260.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues…

Component
2TU
Formula
C9 H12 N2 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

2TU in 2 structures; the first of them:

  • 3SFG · crystal structure of murine norovirus RNA dependent RNA polymerase in complex with… · 2TU A601 · binds LEU187, TRP249, ASP250, LEU301, SER303, THR308, THR309, ASN312 and 4 more
  • 3SFG · Crystal structure of murine norovirus RNA dependent RNA polymerase in complex with… · 2TU A601 · binds LEU187, TRP249, ASP250, LEU301, SER303, THR308, THR309, ASN312 and 4 more

Residues it binds most

ASP 6, THR 6, LEU 6, ASN 6, GLY 6, SER 6, TYR 6, TRP 4 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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