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Ligand · 2SZ

2SZ · 6-(1H-benzimidazol-1-yl)-N-hydroxy-5-[4-({6-[(4-methylpiperazin-1-yl)methyl]pyridin-3-yl}ethynyl)phenyl]pyridine-3-carboxamide

2SZ, 6-(1H-benzimidazol-1-yl)-N-hydroxy-5-[4-({6-[(4-methylpiperazin-1-yl)methyl]pyridin-3-yl}ethynyl)phenyl]pyridine-3-carboxamide (C32 H29 N7 O2, 543.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
2SZ
Formula
C32 H29 N7 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

2SZ in 2 structures; the first of them:

  • 4OKG · LpxC from P.aeruginosa with the inhibitor 6-(benzimidazol-1-yl)-5-[4-[2-[6-[(4-methylpiper… · 2SZ A302 · binds LEU18, HIS19, THR61, MET62, SER63, GLU77, HIS78, THR190 and 16 more
  • 4OKG · Lpxc from P.AERUGINOSA with the inhibitor 6-(benzimidazol-1-yl)-5-[4… · 2SZ A302 · binds LEU18, HIS19, THR61, MET62, SER63, GLU77, HIS78, THR190 and 16 more

Residues it binds most

HIS 4, ALA 4, ASP 4, GLY 4, LEU 4, SER 4, THR 4, VAL 4, MET 4, ARG 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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