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Ligand · 2RJ

2RJ · 2-(2,3-dimethylphenoxy)-4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidine

2RJ, 2-(2,3-dimethylphenoxy)-4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidine (C26 H26 F N5 O, 443.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
2RJ
Formula
C26 H26 F N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

2RJ in 2 structures; the first of them:

  • 4O7B · Crystal structure of the first bromodomain of human BRD4 in complex with SB-284847-BT · 2RJ A201 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, MET105 and 7 more
  • 4O7B · Crystal structure of the first bromodomain of human BRD4 in complex with sb-284847-bt · 2RJ A201 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, MET105 and 7 more

Residues it binds most

MET 2, LEU 2, TYR 2, ASN 2, ASP 2, CYS 2, ILE 2, PHE 2, PRO 2, TRP 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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