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Ligand · 2RF

2RF · 3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophenyl)-1H-pyrrole-2,5-dione

2RF, 3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophenyl)-1H-pyrrole-2,5-dione (C16 H10 Cl2 N2 O3, 349.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
2RF
Formula
C16 H10 Cl2 N2 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

2RF in 2 structures; the first of them:

  • 4O7A · Crystal structure of the first bromodomain of human BRD4 in complex with SB-409514 · 2RF A201 · binds TRP81, PRO82, PHE83, GLN85, VAL87, LEU92, LEU94, TYR97 and 6 more
  • 4O7A · Crystal structure of the first bromodomain of human BRD4 in complex with sb-409514 · 2RF A201 · binds TRP81, PRO82, PHE83, GLN85, VAL87, LEU92, LEU94, TYR97 and 6 more

Residues it binds most

LEU 2, TYR 2, ASN 2, ASP 2, CYS 2, GLN 2, ILE 2, MET 2, PHE 2, PRO 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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