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Ligand · 2P7

2P7 · [3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]-(3-oxidanylazetidin-1-yl)methanone

2P7, [3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]-(3-oxidanylazetidin-1-yl)methanone (C16 H12 F3 I N2 O2, 448.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
2P7
Formula
C16 H12 F3 I N2 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

2P7 in 2 structures; the first of them:

  • 4AN9 · Crystal structures of human MEK1 with carboxamide-based allosteric inhibitor XL518… · 2P7 A1384 · binds LYS97, ILE99, LEU115, LEU118, VAL127, ILE141, MET143, ASP190 and 9 more
  • 4AN9 · Crystal structures of human MEK1 with carboxamide-based allosteric inhibitor XL518… · 2P7 A1384 · binds LYS97, ILE99, LEU115, LEU118, VAL127, ILE141, MET143, ASP190 and 9 more

Residues it binds most

LEU 2, ASP 2, ILE 2, MET 2, VAL 2, ASN 2, CYS 2, GLY 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

  • ACP · Phosphomethylphosphonic acid adenylate ester
  • MG · Magnesium ion

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