Ligand · 2P1
2P1 · N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide
2P1, N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide (C21 H15 F3 N4 O3 S, 460.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…
- Component
- 2P1
- Formula
- C21 H15 F3 N4 O3 S
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
2P1 in 4 structures; the first of them:
- 4O13 · The crystal structure of NAMPT in complex with GNE-618 · 2P1 A601 · binds TYR188, HIS191, PHE193, ARG196, LYS216, GLY217, ASP219, TYR240 and 12 more
- 4O15 · The crystal structure of a mutant NAMPT (S165F) in complex with GNE-618 · 2P1 A601 · binds TYR188, HIS191, PHE193, ARG196, LYS216, GLY217, ASP219, TYR240 and 12 more
- 4O13 · The crystal structure of nampt in complex with gne-618 · 2P1 A601 · binds TYR188, HIS191, PHE193, ARG196, LYS216, GLY217, ASP219, TYR240 and 12 more
- 4O15 · The crystal structure of a mutant nampt (S165F) in complex with gne- 618 · 2P1 A601 · binds TYR188, HIS191, PHE193, ARG196, LYS216, GLY217, ASP219, TYR240 and 12 more
Residues it binds most
TYR 8, ALA 8, ARG 8, ASP 8, ILE 8, PRO 8, SER 8, GLY 8, HIS 8, LYS 8 (residue and the binding sites it lines).
Found with
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