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Ligand · 2NQ

2NQ · N-{2-chloro-5-[4-(morpholin-4-yl)quinolin-6-yl]pyridin-3-yl}-4-fluorobenzenesulfonamide

2NQ, N-{2-chloro-5-[4-(morpholin-4-yl)quinolin-6-yl]pyridin-3-yl}-4-fluorobenzenesulfonamide (C24 H20 Cl F N4 O3 S, 499.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
2NQ
Formula
C24 H20 Cl F N4 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

2NQ in 2 structures; the first of them:

  • 3S2A · Crystal structure of PI3K-gamma in complex with a quinoline inhibitor · 2NQ A1103 · binds MET804, SER806, PRO810, TRP812, ILE831, LYS833, ASP841, TYR867 and 12 more
  • 3S2A · Crystal structure of PI3K-gamma in complex with a quinoline inhibitor · 2NQ A1103 · binds MET804, SER806, PRO810, TRP812, ILE831, LYS833, ASP841, TYR867 and 12 more

Residues it binds most

ILE 2, ASP 2, LYS 2, MET 2, ALA 2, ASN 2, GLU 2, PRO 2, SER 2, THR 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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