GL1X · GenesisL1 explorer

Ligand · 2NF

2NF · [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1yl)- 3-fluoro-,4- hydroxyoxolan-2-yl]methyl phosphate

2NF, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1yl)- 3-fluoro-,4- hydroxyoxolan-2-yl]methyl phosphate (C21 H26 F N7 O13 P2, 665.4 g/mol), in the…

Component
2NF
Formula
C21 H26 F N7 O13 P2
Class
ligand
Structures
4
PDB entries
2

Binding sites

2NF in 4 structures; the first of them:

  • 3GHH · Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally… · 2NF B301 · binds PHE117, TRP118, SER119, LYS120, LYS122, LEU137, GLU138, ASP147 and 11 more
  • 3KOU · Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally… · 2NF A503 · binds PHE117, TRP118, SER119, LYS120, LEU137, SER185, PHE188, SER212 and 3 more
  • 3GHH · Structural insights into the catalytic mechanism of CD38: evidence for a conformationally… · 2NF B301 · binds PHE117, TRP118, SER119, LYS120, LYS122, LEU137, GLU138, ASP147 and 11 more
  • 3KOU · Structural insights into the catalytic mechanism of CD38: evidence for a conformationally… · 2NF A503 · binds PHE117, TRP118, SER119, LYS120, LEU137, SER185, PHE188, SER212 and 3 more

Residues it binds most

SER 6, PHE 6, TRP 6, GLU 6, LYS 6, ILE 6, LEU 6, ARG 2, ASP 4, ALA 2 (residue and the binding sites it lines).

Found with

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.