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Ligand · 2N7

2N7 · (1aR,12bS)-8-cyclohexyl-N-(dimethylsulfamoyl)-11-methoxy-1a-{[(1R,5S)-3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl]carbonyl}-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide

2N7, (1aR,12bS)-8-cyclohexyl-N-(dimethylsulfamoyl)-11-methoxy-1a-{[(1R,5S)-3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl]carbonyl}-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide (C36 H45 N5 O5 S, 659.8 g/mol), in…

Component
2N7
Formula
C36 H45 N5 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

2N7 in 2 structures; the first of them:

  • 4NLD · Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with… · 2N7 A601 · binds LEU392, ALA393, ALA395, ALA396, THR399, ALA400, ILE424, LEU425 and 8 more
  • 4NLD · Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with… · 2N7 A601 · binds LEU392, ALA393, ALA395, ALA396, THR399, ALA400, ILE424, LEU425 and 8 more

Residues it binds most

ALA 2, LEU 2, ARG 2, GLY 2, HIS 2, ILE 2, PHE 2, PRO 2, THR 2, TRP 2 (residue and the binding sites it lines).

Found with

  • 2N5 · 2-(4-fluorophenyl)-N-methyl-6-[(methylsulfonyl)amino]-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide
  • SO4 · Sulfate ion
  • BOG · octyl beta-D-glucopyranoside

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